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Issachar Conference Group

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A mouse (PL: mice) is a small rodent. Characteristically, mice are known to have a pointed snout, small rounded ears, a body-length scaly tail, and a high breeding rate. The best known mouse species is the common house mouse (Mus musculus). Mice are also popular as pets. In some places, certain kinds of field mice are locally common. They are known to invade homes for food and shelter.



Mice are typically distinguished from rats by their size. Generally, when a muroid rodent is discovered, its common name includes the term mouse if it is smaller, or rat if it is larger. The common terms rat and mouse are not taxonomically specific. Typical mice are classified in the genus Mus, but the term mouse is not confined to members of Mus and can also apply to species from other genera such as the deer mouse, Peromyscus.

Domestic mice sold as pets often differ substantially in size from the common house mouse. This is attributable to breeding and different conditions in the wild. The best-known strain of mouse is the white lab mouse. It has more uniform traits that are appropriate to its use in research.

Cats, wild dogs, foxes, birds of prey, snakes and even certain kinds of arthropods have been known to prey heavily upon mice. Despite this, mice populations remain plentiful. Due to its remarkable adaptability to almost any environment, the mouse is one of the most successful mammalian genera living on Earth today.

In certain contexts, mice can be considered vermin. Vermin are a major source of crop damage,[1] as they are known to cause structural damage and spread disease. Mice spread disease through their feces and are often carriers of parasites.[2] In North America, breathing dust that has come in contact with mouse excrement has been linked to hantavirus, which may lead to hantavirus pulmonary syndrome (HPS).

In nature, mice are largely herbivores, consuming any kind of fruit or grain from plants.[9] However, mice adapt well to urban areas and are known for eating almost all types of food scraps. In captivity, mice are commonly fed commercial pelleted mouse diet. These diets are nutritionally complete, but they still need a large variety of vegetables.

Mice are common experimental animals in laboratory research of biology and psychology fields primarily because they are mammals, and also because they share a high degree of homology with humans. They are the most commonly used mammalian model organism, more common than rats. The mouse genome has been sequenced, and virtually all mouse genes have human homologs. The mouse has approximately 2.7 billion base pairs and 20 pairs of chromosomes.[12]They can also be manipulated in ways that are illegal with humans, although animal rights activists often object. A knockout mouse is a genetically modified mouse that has had one or more of its genes made inoperable through a gene knockout.

Many people buy mice as companion pets. They can be playful, loving and can grow used to being handled. Like pet rats, pet mice should not be left unsupervised outside as they have many natural predators, including (but not limited to) birds, snakes, lizards, cats, and dogs. Male mice tend to have a stronger odor than the females. However, mice are careful groomers and as pets they never need bathing. Well looked-after mice can make ideal pets. Some common mouse care products are:

Humans have eaten mice since prehistoric times. In Victorian Britain, fried mice were still given to children as a folk remedy for bed-wetting;[15] while Jared Diamond reports creamed mice being used in England as a dietary supplement during WW II rationing.[16] Mice are a delicacy throughout eastern Zambia and northern Malawi,[17] where they are a seasonal source of protein. Field rat is a popular food in Vietnam and neighboring countries.[18] In many countries, however, mouse is no longer a food item.

Prescribed cures in Ancient Egypt included mice as medicine.[19] In Ancient Egypt, when infants were ill, mice were eaten as treatment by their mothers.[20][21] It was believed that mouse eating by the mother would help heal the baby who was ill.[22][23][24][25][26]

The Microsoft Mouse and Keyboard Center is an app that helps you make the most out of your Microsoft keyboard and mouse. Mouse and Keyboard Center helps you personalize and customize how you work on your PC.

Double press the left Ctrl key or shake the mouse to activate a spotlight that focuses on the cursor's position. Click the mouse or press any keyboard key to dismiss it. If you move the mouse while the spotlight is active, the spotlight will dismiss on its own shortly after the mouse stops moving.

With a mouse, you can also choose a behavior for a secondary click. In iPadOS, a secondary click acts like a long press on the iPad touchscreen, or a Control-click (or right-click) on a Mac. For example, when you use a secondary mouse click on an iPad app icon, its contextual menu appears.

Select Secondary Click, then choose whether you want a secondary click to happen when you click on the left or right side of your mouse, or not at all. You can also perform a secondary click on iPad with any pointing device by holding the Control key as you click.

Don't see the onscreen keyboard when you have a trackpad or mouse connected? Tap the keyboard button in the lower-right corner of the screen. In the menu that appears, tap the show keyboard button . To hide the software keyboard, tap the dismiss button .

We and our collaborators have used short-read sequencing to identify SNPs, indels, and structural variations relative to the C57BL/6J mouse reference genome. The strains that have been sequenced and are in our variation catalog are:

NOTE: These assembled chromosomes are released as unpublished, preliminary and incomplete sequences and as such they have not yet been submitted to the accessioned in the public genome sequence repositories (INSDC). The assembled sequences will be fully accessioned in public repositories at the time of publication. These data are released in accordance with the Fort Lauderdale agreement and Toronto agreements. As producers of these data we reserve the right to be the first to publish a genome-wide analysis of the data we have generated. The pre-publication data that we release are embargoed for publication except for analyses of single chromosomes in single strains or single gene loci across multiple strains. We strongly encourage researchers to contact us ( if there are any queries about referencing or publishing analysis based on pre-publication data. We expect to accession and publish the genome sequences and strain specific gene annotation in mid-late 2016.

The MJ-3 is programmable, making it ideal for repetitive IT or gaming tasks. You can create customized scripts with programmed mouse movement, mouse clicks, and keystrokes. The smaller size of the MJ-3 keeps it out of the way and is unobtrusive when installed.

To automate repetitive or predictable tasks commonly found in IT operations or fun pursuits like gaming, the plug-and-use USB device can be programmed with your scripts to play back keystrokes, mouse movements, and mouse clicks.

The Key Largo cotton mouse is the largest of all subspecies of cotton mouse found in peninsular Florida (U.S. Fish & Wildlife Service, 1999). This cotton mouse subspecies can reach a body length of seven inches (17.9 centimeters) with a tail length of three inches (7.7 centimeters). Key Largo cotton mice have a dark hazel back with reddish brown sides, a white belly, white feet, and a tail that is brown on top and white on the bottom (Florida Natural Areas Inventory 2001).

The diet of the Key Largo cotton mouse consists of berries, seeds, nuts, and insects (M. Tucker pers. comm. 2012). Berries from tropical hardwood hammock trees and shrubs may be an important food supply for the Key Largo cotton mouse (U.S. Fish & Wildlife Service 1999).

The Key Largo population of the cotton mouse constructs nests in hollow tree stumps, fallen logs, and crevices in limestone outcrops (Barbour and Humphrey 1982). Breeding occurs throughout the year with a peak breeding season in the fall and early spring (U.S. Fish & Wildlife Service 1999, Bigler and Jenkins 1975). The average litter size is 3 young per litter, with three to four litters per year (Bigler and Jenkins 1975).

Habitat loss and fragmentation have isolated populations of the Key Largo cotton mouse, which increases the severity of all other threats. Isolated populations have reduced gene flow which leads to lower genetic diversity, and potentially lower survival (U.S. Fish & Wildlife Service, 2009). Fragmentation along its small range also makes the Key Largo cotton mouse vulnerable to tropical storms and hurricanes. Trash dumping (a result of increased urbanization) also threatens the Key Largo cotton mouse, leading to an increased population of black rats (Rattus rattus). Black rats may out-compete the Key Largo cotton mouse for food and other resources (U.S. Fish & Wildlife Service, 1999). Sea level rise is an impending threat to the Key Largo cotton mouse population.

Barbour, D.B. and S.R. Humphrey. 1982. Status and habitat of the Key Largo woodrat and cotton mouse (Neotoma floridana smalli and Peromyscus gossypinusallapaticola). Journal of Mammalogy 63(1): 144-148.

U.S. Fish and Wildlife Service. 2009. Key Largo cotton mouse (Peromyscus gossypinus allapaticola) 5-Year review: summary and evaluation. U.S. Fish & Wildlife Service, Vero Beach, FL. _year_review/doc2378.pdf

  • Genetically engineered mouse models (GEMMs) have become indispensable tools in nearly all fields of biomedical research. For example, in cancer research their utility ranges from studies of the basic biology of tumorigenesis and progression to the creation of genetically accurate tumor models for the evaluation of novel therapeutic approaches. The objectives of TGKO are to: Facilitate the development of new GEMMs (including transgenic, knockout, conditional knockout and knock-in mice) using both conventional and CRISPR/Cas9-based technologies

  • Provide a full range of support services to facilitate the use of these models, including breeding colony management, mouse line rederivation, embryo and sperm cryopreservation and cryorecovery

  • Offer expert consultation on the development and use of GEMMs



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